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Article

Quantifying in vivo somatic mutations using transgenic mouse model systems.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2005

Swiger Roy R

Abstract excerpt

This chapter describes the use of the bacteriophage cII positive selection assay with the MutaMouse transgenic model system. The assay is similar to others involving a transgenic target, including the cII and lacI assays in the Big Blue(R) Mouse, lacZ in the MutaMouse, and the gpt delta assay. Briefly, high-molecular-weight DNA is purified from the tissue of interest and used as substrate during in vitro...

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Identifiers

PMID: 15502219
DOI: 10.1385/1-59259-840-4:145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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