Article
Hamster and rat fetal cells have low spontaneous mutation frequencies and rates.
Mutation research - 1 Jul 2001
Donovan P J, Smith G T, Riggs C W
Abstract excerpt
Somatic cells of whole Syrian hamster fetuses (gestation day 13) were isolated and tested by an in vivo/in vitro mutation assay for spontaneous mutation frequencies using independent 6-thioguanine (6-TG), diphtheria toxin (DT), and ouabain mutation selection systems. Optimum conditions were ascertained. For 6-TG mutants, a total of 21 mutants were found in cells from 24 litters on 1993 plates, for an overall...
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