Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic polymorphism of CYP2D6 and CYP2C19 in east- and southern African populations including psychiatric patients.

European journal of clinical pharmacology - 1 Apr 2001

Dandara C, Masimirembwa C M, Magimba A, Sayi J, Kaaya S, Sommers D K, Snyman J R, Hasler J A

Abstract excerpt

OBJECTIVES: The study was carried out to investigate the distribution of cytochrome P450 2D6 (CYP2D6) and CYP2C19 genotype frequencies in three African populations and to compare these frequencies between healthy individuals and psychiatric patients. METHODS: Three hundred and eighty-four subjects from South Africa (Venda), Tanzania, and Zimbabwe who consented to the study were genotyped for CYP2D6 (CYP2D6*1, *2,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Africa, Eastern
Share to Africa, Southern

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Aryl Hydrocarbon Hydroxylases

Share to Cytochrome P-450 CYP2C19

Share to Cytochrome P-450 CYP2D6

Share to Cytochrome P-450 Enzyme System

Share to Mental Disorders

Share to Mixed Function Oxygenases

Source

Identifiers

PMID: 11372584
DOI: 10.1007/s002280100282

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic polymorphism of CYP2D6 and CYP2C19 in east- and southern African populations including psychiatric patients.PMID 11372584Read ↗

Distribution of alleles, genotypes and haplotypes of the CYP2B6 (rs3745274; rs2279343) and CYP3A4 (rs2740574) genes in the Malian population: Implication for pharmacogenetics.Semantic proximity Read ↗

Meta-analysis of probability estimates of worldwide variation of CYP2D6 and CYP2C19.Semantic proximity Read ↗

African Genetic Diversity: Implications for Cytochrome P450-mediated Drug Metabolism and Drug DevelopmentSemantic proximity Read ↗

Phenotypes and genotypes for CYP2D6 and CYP2C19 in a black Tanzanian population.Semantic proximity Read ↗

Relationship between metabolic phenotypes and genotypes of CYP1A2 and CYP2A6 in the Nigerian population.Semantic proximity Read ↗

Genetic polymorphism of drug metabolising enzymes in African populations: implications for the use of neuroleptics and antidepressants.Semantic proximity Read ↗

CYP2C19 genetic polymorphism in Saudi Arabians.Semantic proximity Read ↗

Prevalence of five pharmacologically most important CYP2C9 and CYP2C19 allelic variants in the population from the Republic of Srpska in Bosnia and Herzegovina.Semantic proximity Read ↗

Human Cytochrome P450 1, 2, 3 Families as Pharmacogenes with Emphases on Their Antimalarial and Antituberculosis Drugs and Prevalent African Alleles.Semantic proximity Read ↗

CYP2B6 poor metaboliser alleles involved in efavirenz and nevirapine metabolism: CYP2B6*9 and CYP2B6*18 distribution in HIV-exposed subjects from Dschang, Western Cameroon.Semantic proximity Read ↗

Distribution of CYP2D6 and CYP2C19 polymorphisms associated with poor metabolizer phenotype in five Amerindian groups and western Mestizos from Mexico.Semantic proximity Read ↗

[Genotyping of CYP2D6 and CYP2C19].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.