Article
Relationship between metabolic phenotypes and genotypes of CYP1A2 and CYP2A6 in the Nigerian population.
Drug metabolism and personalized therapy - 1 Mar 2017
Adehin Ayorinde, Bolaji Oluseye O, Maggo Simran, Kennedy Martin A
Abstract excerpt
BACKGROUND: CYP1A2 and CYP2A6 are polymorphic drug-metabolising enzymes that are also implicated in the activation of procarcinogens in humans. Some of their alleles and haplotypes, often varied in prevalence across populations, are thought to influence activity despite the known contribution of environmental factors. This study assessed the potential influence of some genetic variants of CYP1A2 and CYP2A6 on...
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