Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human Cytochrome P450 1, 2, 3 Families as Pharmacogenes with Emphases on Their Antimalarial and Antituberculosis Drugs and Prevalent African Alleles.

International journal of molecular sciences - 8 Feb 2023

Chamboko Chiratidzo R, Veldman Wayde, Tata Rolland Bantar, Schoeberl Birgit, Tastan Bishop Özlem

Abstract excerpt

Precision medicine gives individuals tailored medical treatment, with the genotype determining the therapeutic strategy, the appropriate dosage, and the likelihood of benefit or toxicity. Cytochrome P450 (CYP) enzyme families 1, 2, and 3 play a pivotal role in eliminating most drugs. Factors that affect CYP function and expression have a major impact on treatment outcomes. Therefore, polymorphisms of these...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimalarials
Share to Antitubercular Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2B6

Share to Cytochrome P-450 CYP2C19

Share to Cytochrome P-450 CYP2C8

Share to Cytochrome P-450 CYP2C9

Share to Cytochrome P-450 CYP2D6

Share to Cytochrome P-450 CYP3A

Source

Open in PubMed Open full text

Identifiers

PMID: 36834793
DOI: 10.3390/ijms24043383
PMCID: PMC9961538

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human Cytochrome P450 1, 2, 3 Families as Pharmacogenes with Emphases on Their Antimalarial and Antituberculosis Drugs and Prevalent African Alleles.PMID 36834793Read ↗

African variation at Cytochrome P450 genesSemantic proximity Read ↗

African Genetic Diversity: Implications for Cytochrome P450-mediated Drug Metabolism and Drug DevelopmentSemantic proximity Read ↗

Cytochrome P450 pharmacogenetics in African populations.Semantic proximity Read ↗

Polymorphisms in Cytochrome P450 genes: implications for Plasmodium vivax malaria treatment in Brazil.Semantic proximity Read ↗

Cytochrome P450 enzymes and genotype-guided drug therapy.Semantic proximity Read ↗

Meta-analysis of the global distribution of clinically relevant CYP2C8 alleles and their inferred functional consequences.Semantic proximity Read ↗

Cytochrome P450 in Pharmacogenetics: An Update.Semantic proximity Read ↗

Polymorphic cytochrome P450 enzymes (CYPs) and their role in personalized therapy.Semantic proximity Read ↗

Polymorphic CYP2B6: molecular mechanisms and emerging clinical significance.Semantic proximity Read ↗

Cytochrome P450 Drug Metabolizing Enzymes in Roma Population Samples: Systematic Review of the Literature.Semantic proximity Read ↗

Cytochrome P450 single nucleotide polymorphisms in an indigenous Tanzanian population: a concern about the metabolism of artemisinin-based combinations.Semantic proximity Read ↗

Cytochromes p450: roles in diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.