Article
CYP2B6 poor metaboliser alleles involved in efavirenz and nevirapine metabolism: CYP2B6*9 and CYP2B6*18 distribution in HIV-exposed subjects from Dschang, Western Cameroon.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Oct 2015
Paganotti Giacomo Maria, Russo Gianluca, Sobze Martin Sanou, Mayaka George Bouting, Muthoga Charles Waithaka, Tawe Leabaneng, Martinelli Axel, Romano Rita, Vullo Vincenzo
Abstract excerpt
The prescription of patients' tailored anti-infectious treatments is the ultimate goal of pharmacogenetics/genomics applied to antimicrobial treatments, providing a basis for personalized medicine. Despite the efforts to screen Africans for alleles underlying defective metabolism for a panel of different drugs, still more research is necessary to clarify the interplay between host genetic variation and...
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