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CYP2C19 genetic polymorphism in Saudi Arabians.

Basic & clinical pharmacology & toxicology - 1 Jan 2013

Al-Jenoobi Fahad I, Alkharfy Khalid M, Alghamdi Amal M, Bagulb Khawla M, Al-Mohizea Abdullah M, Al-Muhsen Saleh, Halwani Rabih, Parvez Mohammad Khalid, Al-Dosari Mohammed S

Abstract excerpt

The main objective of this study was to evaluate CYP2C19 genetic polymorphism in a Saudi Arabian population by determining the frequencies of CYP2C19*2, *3, *4, *6, *7 and *17 alleles and their relevant genotypes. Genomic DNA was isolated from 192 healthy Saudi Arabians, representing different geographical regions, and genotyping of the selected CYP2C19 variants was carried out by direct sequencing after PCR...

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Aryl Hydrocarbon Hydroxylases
Cytochrome P-450 CYP2C19
Gene Frequency
Genotype
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22747643
DOI: 10.1111/j.1742-7843.2012.00919.x

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