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Article

Phenotypes and genotypes for CYP2D6 and CYP2C19 in a black Tanzanian population.

British journal of clinical pharmacology - 1 Sept 1999

Bathum L, Skjelbo E, Mutabingwa T K, Madsen H, Hørder M, Brøsen K

Abstract excerpt

AIMS: CYP2D6 and CYP2C19 are polymorphically expressed enzymes that show marked interindividual and interethnic variation. The aim of this study was to determine the frequency of the defective alleles in CYP2D6 and CYP2C19 in Africans and to test whether the genotype for CYP2C19 is better correlated with the proguanil/cylcoguanil ratio than the mephenytoin S/R ratio. METHODS: Two hundred and sixteen black...

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Identifiers

PMID: 10510152
DOI: 10.1046/j.1365-2125.1999.00019.x
PMCID: PMC2014329

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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