Article
[Genotyping of CYP2D6 and CYP2C19].
Casopis lekaru ceskych - 1 Jan 2007
Slanar O, Drazd'áková M, Babiárová K, Pechandová K, Buzková H, Perlík F, Zima T
Abstract excerpt
BACKGROUND: Polymorphisms in drug metabolizing enzymes are considered as a major factor influencing the incidence of adverse drug reactions or failure of pharmacotherapy. Our aim was to compare the distribution of functional polymorphisms in the genes CYP2D6 and CYP2C19 between healthy control group and of patients reffered to our department due to adverse drug reactions or insufficient efficacy of a treatment....
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