Article
Obesity and elevated plasma leptin concentration in oMT1A-o growth hormone transgenic mice.
Obesity research - 1 Jan 2001
Oberbauer A M, Runstadler J A, Murray J D, Havel P J
Abstract excerpt
OBJECTIVE: This study was undertaken to evaluate plasma leptin concentration in the regulatable ovine metallothionein-ovine growth hormone (oMT1a-oGH) transgenic (TG) mouse model of obesity. RESEARCH METHODS AND PROCEDURES: Transgene stimulus (zinc) was provided at 21 days of age to male and female wild-type (WT) and TG mice. Plasma leptin concentrations were measured by radioimmunoassay at 42, 63, 84, and 105...
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