Article

Increased capacity to maintain glucose homeostasis in a transgenic mouse expressing human but not mouse growth hormone with developing high fat diet-related insulin resistance, steatosis and adipose dysfunction

2024-02-23

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Differences in primate and non-primate growth hormone (GH) genes can affect their regulation and function. This includes the ability of human (h) but not mouse (m) GH to bind the prolactin (PRL) receptor (PRLR) as well as the GH receptor (GHR). Potential differential effects were assessed in male hGH- or mGH-expressing mice and fed high fat diet (HFD) versus regular chow die...

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Literature Corpus work: fef31bc5-8eae-5eca-942a-c81739aa3b14
DOI: 10.1101/2024.02.21.581281

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Increased capacity to maintain glucose homeostasis in a transgenic mouse expressing human but not mouse growth hormone with developing high fat diet-related insulin resistance, steatosis and adipose dysfunctionDOI 10.1101/2024.02.21.581281Read

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