Article
Body composition of inactivated growth hormone (oMt1a-oGH) transgenic mice: generation of an obese phenotype.
Growth, development, and aging : GDA - 1 Jan 2000
Oberbauer A M, Stern J S, Johnson P R, Horwitz B A, German J B, Phinney S D, Beermann D H, Pomp D, Murray J D
Abstract excerpt
The consequences of a 42 d exposure to elevated growth hormone (GH) on adipose tissue were assessed using the regulatable ovine metallothionein- ovine GH (oMt1a-oGH) transgene in male and female GH transgenic (TG) mice. Activation of transgene expression at 21 d of age followed by inactivation of transgene expression at 63 d of age (TG-on/off) increased individual white adipose tissue (WAT) depots and total body...
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