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Article

Increased expression of transthyretin in leptin-deficient ob/ob mice is not causative for their major phenotypic abnormalities.

Journal of neuroendocrinology - 1 Jan 2013

Rendenbach C, Ganswindt S, Seitz S, Barvencik F, Huebner A K, Baranowsky A, Streichert T, Niemeier A, Heeren J, Amling M, Bartelt A, Schinke T

Abstract excerpt

The hormone leptin is a critical regulator of adipogenesis and energy metabolism. Similarly, leptin-deficient ob/ob mice display various metabolic abnormalities, including not only obesity and insulin resistance, but also hypogonadism and high bone mass. By genome-wide expression analysis using h...

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Identifiers

PMID: 22849972
DOI: 10.1111/j.1365-2826.2012.02366.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22849972-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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