Article
The response of transgenic mice to beta-adrenergic agonist administration is different from that of normal mice.
Journal of animal science - 1 Aug 1997
Sharma A K, Lee Y B, Murray J D
Abstract excerpt
Eighteen transgenic mice carrying an ovine metallothionein la-ovine growth hormone (oMTla-oGH) transgene and 18 littermate normal mice were used to investigate the effects of transgene expression and clenbuterol administration on growth performance and skeletal muscle characteristics. The oGH transgene was activated from 21 d of age, and half of the mice were fed 15 ppm clenbuterol from 42 to 70 d of age. All...
Topics
- Adrenergic beta-Agonists
- Aging
- Animals
- Body Weight
- Cathepsins
- Clenbuterol
- DNA
- Female
- Genotype
- Growth Hormone
- Male
- Metallothionein
- Mice
- Mice, Inbred C57BL
- Mice, Inbred CBA
- Mice, Transgenic
- Muscle Development
- Muscle Fibers, Skeletal
