Article
Transformation of sib-pair values for the Haseman-Elston method.
American journal of human genetics - 1 May 2001
Wang D, Lin S, Cheng R, Gao X, Wright F A
Abstract excerpt
The squared sib-pair phenotype difference (SQD) has been used as a dependent variable in the Haseman-Elston (H-E) regression quantitative-trait locus (QTL) linkage method, but it has been shown that the SQD does not make full use of linkage information. In this study, we examine the efficiency of SQD in H-E regression compared to other proposed functions of the sib-pair phenotypes. A new function of sib-pair...
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