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Article

A sib-pair approach to interval mapping of quantitative trait loci.

American journal of human genetics - 1 Jun 1994

Fulker D W, Cardon L R

Abstract excerpt

An interval mapping procedure based on the sib-pair method of Haseman and Elston is developed, and simulation studies are carried out to explore its properties. The procedure is analogous to other interval mapping procedures used with experimental material, such as plants and animals, and yields very similar results in terms of the location and effect size of a quantitative trait locus (QTL). The procedure offers...

Topics

Alleles
Chromosome Mapping
Chromosomes, Human
Genetic Linkage
Genetic Markers
Genotype
Humans
Models, Genetic
Models, Statistical

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8198132
PMCID: PMC1918198

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8198132-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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