Article
Selection and subsequent analysis of sib pair data for QTL detection.
Genetical research - 1 Oct 2001
Chatziplis D G, Hamann H, Haley C S
Abstract excerpt
Haseman and Elston (1972) developed a robust regression method for the detection of linkage between a marker and a quantitative trait locus (QTL) using sib pair data. The principle underlying this method is that the difference in phenotypes between pairs of sibs becomes larger as they share a decreasing number of alleles at a particular QTL identical by descent (IBD) from their parents. In this case,...
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