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Article

Multipoint linkage analysis of the pseudoautosomal regions, using affected sibling pairs.

American journal of human genetics - 1 Aug 2000

Dupuis J, Van Eerdewegh P

Abstract excerpt

Affected sibling pairs are often the design of choice in linkage-analysis studies with the goal of identifying the genes that increase susceptibility to complex diseases. Methods for multipoint analysis based on sibling amount of sharing that is identical by descent are widely available, for both autosomal and X-linked markers. Such methods have the advantage of making few assumptions about the mode of...

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PMID: 10869236
DOI: 10.1086/303008
PMCID: PMC1287190

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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