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Article

Equivalence between Haseman-Elston and variance-components linkage analyses for sib pairs.

American journal of human genetics - 1 Jun 2001

Sham P C, Purcell S

Abstract excerpt

The Haseman-Elston regression method offers a simpler alternative to variance-components (VC) models, for the linkage analysis of quantitative traits. However, even the "revisited" method, which uses the cross-product--rather than the squared difference--in sib trait values, is, in general, less powerful than VC models. In this report, we clarify the relative efficiencies of existing Haseman-Elston methods and...

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Identifiers

PMID: 11353401
DOI: 10.1086/320593
PMCID: PMC1226141

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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