Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Quantitative trait linkage analysis by generalized estimating equations: unification of variance components and Haseman-Elston regression.

Genetic epidemiology - 1 May 2004

Chen Wei-Min, Broman Karl W, Liang Kung-Yee

Abstract excerpt

Two of the major approaches for linkage analysis with quantitative traits in humans include variance components and Haseman-Elston regression. Previously, these were viewed as quite separate methods. We describe a general model, fit by use of generalized estimating equations (GEE), for which the variance components and Haseman-Elston methods (including many of the extensions to the original Haseman-Elston method)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Chromosome Mapping
Share to Chromosomes, Human

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Linkage

Share to Models, Genetic

Share to Models, Statistical

Share to Pedigree

Share to Quantitative Trait, Heritable

Source

Identifiers

PMID: 15095386
DOI: 10.1002/gepi.10315

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Quantitative trait linkage analysis by generalized estimating equations: unification of variance components and Haseman-Elston regression.PMID 15095386Read ↗

Equivalence between Haseman-Elston and variance-components linkage analyses for sib pairs.Semantic proximity Read ↗

A unified Haseman-Elston method for testing linkage with quantitative traits.Semantic proximity Read ↗

Gamma regression improves Haseman-Elston and variance components linkage analysis for sib-pairs.Semantic proximity Read ↗

Linkage analysis: principles and methods for the analysis of human quantitative traits.Semantic proximity Read ↗

Score test for detecting linkage to quantitative traits.Semantic proximity Read ↗

The Garden of Forking Paths: Reinterpreting Haseman-Elston Regression for a Genotype-by-Environment Model.Semantic proximity Read ↗

Confidence intervals for heritability via Haseman-Elston regression.Semantic proximity Read ↗

Extension of the Haseman-Elston regression model to longitudinal data.Semantic proximity Read ↗

Power of a simplified multivariate test for genetic linkage.Semantic proximity Read ↗

Extension of the Haseman-Elston method to multiple alleles and multiple loci: theory and practice for candidate genes.Semantic proximity Read ↗

A quantitative linkage score for an association study following a linkage analysis.Semantic proximity Read ↗

Information perspectives of the Haseman-Elston method.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.