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Genomic Characterization of Esophageal Squamous Cell Carcinoma from a High-Risk Population in China

7 Jul 2009

Abstract excerpt

Genomic instability plays an important role in most human cancers. To characterize genomic instability in esophageal squamous cell carcinoma (ESCC), we examined loss of heterozygosity (LOH), copy number (CN) loss, CN gain, and gene expression using the Affymetrix GeneChip Human Mapping 500K (n = 30 cases) and Human U133A (n = 17 cases) arrays in ESCC cases from a high-risk region of China. We found that genomic...

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PMID: 19584285
DOI: 10.1158/0008-5472.can-08-4622

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