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Article

The sequence requirements for a functional Escherichia coli replication origin are different for the chromosome and a minichromosome.

Molecular microbiology - 1 Apr 2001

Weigel C, Messer W, Preiss S, Welzeck M, Morigen, Boye E

Abstract excerpt

We have developed a simple three-step method for transferring oriC mutations from plasmids to the Escherichia coli chromosome. Ten oriC mutations were used to replace the wild-type chromosomal origin of a recBCsbcB host by recombination. The mutations were subsequently transferred to a wild-type host by transduction. oriC mutants with a mutated DnaA box R1 were not obtained, suggesting that R1 is essential for...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11309131
DOI: 10.1046/j.1365-2958.2001.02409.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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