Article
DNA damage-inducible replication of the Escherichia coli chromosome is initiated at separable sites within the minimal oriC.
Journal of molecular biology - 4 Feb 1994
Asai T, Imai M, Kogoma T
Abstract excerpt
When Escherichia coli cells are subjected to genetic stress by exposure to agents or conditions that transiently block DNA replication, the mode of DNA replication is profoundly altered. One of the alterations is the induction of inducible stable DNA replication (iSDR) that does not require the initiator protein, DnaA, and occurs despite the presence of rifampin and chloramphenicol, which inhibit the initiation...
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