Article
Identification of oriT and a recombination hot spot in the IncA/C plasmid backbone.
Scientific reports - 6 Sept 2017
Hegyi Anna, Szabó Mónika, Olasz Ferenc, Kiss János
Abstract excerpt
Dissemination of multiresistance has been accelerating among pathogenic bacteria in recent decades. The broad host-range conjugative plasmids of the IncA/C family are effective vehicles of resistance determinants in Gram-negative bacteria. Although more than 150 family members have been sequenced to date, their conjugation system and other functions encoded by the conserved plasmid backbone have been poorly...
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