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Article

Multiple replication origins of Halobacterium sp. strain NRC-1: properties of the conserved orc7-dependent oriC1.

Journal of bacteriology - 1 Aug 2009

Coker James A, DasSarma Priya, Capes Melinda, Wallace Tammitia, McGarrity Karen, Gessler Rachael, Liu Jingfang, Xiang Hua, Tatusov Roman, Berquist Brian R, DasSarma Shiladitya

Abstract excerpt

The eukaryote-like DNA replication system of the model haloarchaeon Halobacterium NRC-1 is encoded within a circular chromosome and two large megaplasmids or minichromosomes, pNRC100 and pNRC200. We previously showed by genetic analysis that 2 (orc2 and orc10) of the 10 genes coding for Orc-Cdc6 replication initiator proteins were essential, while a third (orc7), located near a highly conserved autonomously...

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Identifiers

PMID: 19502403
DOI: 10.1128/JB.00210-09
PMCID: PMC2725591

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Source receipt: pubmed, retrieved 7 Sept 2026.

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