Article
A novel dnaC mutation that suppresses priB rep mutant phenotypes in Escherichia coli K-12.
Molecular microbiology - 1 May 2006
Boonsombat Ruethairat, Yeh Su-Ping, Milne Amy, Sandler Steven J
Abstract excerpt
The loading of a replisome in prokaryotic and eukaryotic cells at an origin of DNA replication and during replication restart is a highly ordered and regulated process. During replication restart in Escherichia coli, the PriA, PriB, PriC, DnaT and Rep proteins form multiple pathways that bind to repaired replication forks. These complexes are then recognized by DnaC as sites to load DnaB, the replicative...
Topics
- DNA Replication
- DNA-Binding Proteins
- Escherichia coli
- Escherichia coli Proteins
- Genes, Dominant
- Genes, Lethal
- Genes, Recessive
- Mutant Proteins
- Mutation
- Phenotype
- Suppression, Genetic
