Article
Mutations in the DnaA binding sites of the replication origin of Escherichia coli.
Molecular & general genetics : MGG - 1 May 1992
Holz A, Schaefer C, Gille H, Jueterbock W R, Messer W
Abstract excerpt
Mutations (base changes) were introduced into the four DnaA binding sites (DnaA boxes) of the Escherichia coli replication origin, oriC. Mutations in a single DnaA box did not impair the ability of these origins to replicate in vivo and in vitro. A combination of mutations in two DnaA boxes, R1 a...
Topics
- Bacterial Proteins
- Base Sequence
- Binding Sites
- Chromosomes, Bacterial
- Cloning, Molecular
- DNA Fingerprinting
- DNA Replication
- DNA, Bacterial
- DNA-Binding Proteins
- Escherichia coli
- Molecular Sequence Data
- Mutation
- Plasmids