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Establishment and Maintenance of DNA Methylation Patterns in Mouse Ndn : Implications for Maintenance of Imprinting in Target Genes of the Imprinting Center

1 Apr 2001

Abstract excerpt

Ndn is located on chromosome 7C, an imprinted region of the mouse genome. Imprinting of Ndn and adjacent paternally expressed genes is regulated by a regional imprinting control element known as the imprinting center (IC). An IC also controls imprint resetting of target genes in the region of conserved synteny on human chromosome 15q11-q13, which is deleted or rearranged in the neurodevelopmental disorder...

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PMID: 11259587
DOI: 10.1128/mcb.21.7.2384-2392.2001

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