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The specification of imprints in mammals

18 Jun 2014

Abstract excerpt

At the heart of genomic imprinting in mammals are imprinting control regions (ICRs), which are the discrete genetic elements that confer imprinted monoallelic expression to several genes in imprinted gene clusters. A characteristic of the known ICRs is that they acquire different epigenetic states, exemplified by differences in DNA methylation, in the sperm and egg, and these imprint marks remain on the sperm-...

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PMID: 24939713
DOI: 10.1038/hdy.2014.54

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