Article
Structure of the imprinted mouse Snrpn gene and establishment of its parental-specific methylation pattern.
Proceedings of the National Academy of Sciences of the United States of America - 16 Sept 1997
Shemer R, Birger Y, Riggs A D, Razin A
Abstract excerpt
The mouse Snrpn gene encodes the Smn protein, which is involved in RNA splicing. The gene maps to a region in the central part of chromosome 7 that is syntenic to the Prader-Willi/Angelman syndromes (PWS-AS) region on human chromosome 15q11-q13. The mouse gene, like its human counterpart, is impr...
Topics
- Alleles
- Animals
- Autoantigens
- Base Sequence
- Cells, Cultured
- DNA Methylation
- DNA, Complementary
- Embryonic Development
- Female
- Fertilization
- Genomic Imprinting
- Male
- Mice
- Molecular Sequence Data
- Pregnancy
- Ribonucleoproteins, Small Nuclear
- snRNP Core Proteins