Article
Identification of novel imprinted genes in a genome-wide screen for maternal methylation.
Genome research - 1 Apr 2003
Smith Rachel J, Dean Wendy, Konfortova Galia, Kelsey Gavin
Abstract excerpt
A characteristic of imprinted genes is that the maternal and paternal alleles show differences in methylation. To perform a genome-wide screen for novel imprinted loci, we applied methylation-sensitive representational difference analysis (Me-RDA) to parthenogenetic mouse embryos, to identify differentially methylated regions (DMRs) methylated specifically on the maternal allele. We isolated a total of 26...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
