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Article

Endoplasmic reticulum/cytosolic localization of von Hippel-Lindau gene products is mediated by a 64-amino acid region.

International journal of cancer - 15 Feb 2001

Schoenfeld A R, Davidowitz E J, Burk R D

Abstract excerpt

Inactivation of the von Hippel-Lindau (VHL) tumor-suppressor gene causes both the familial cancer syndrome VHL disease and corresponding sporadic tumor types, including renal-cell carcinoma. Subcellular localization of VHL gene products was determined by indirect immunofluorescence. Both native and exogenously expressed VHL proteins displayed a cytoplasmic peri-nuclear immunostaining pattern, which co-localized...

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Source

Identifiers

PMID: 11251966
DOI: 10.1002/1097-0215(20010215)91:4<457::aid-ijc1072>3.0.co;2-p

Genes

VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Endoplasmic reticulum/cytosolic localization of von Hippel-Lindau gene products is mediated by a 64-amino acid region.PMID 11251966Read ↗

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Phosphorylation-dependent cleavage regulates von Hippel Lindau proteostasis and function.Semantic proximity Read ↗

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