Article
Association between p53 immunostaining and cigarette smoking in squamous cell carcinoma of the esophagus.
Japanese journal of clinical oncology - 1 Oct 2000
Mizobuchi S, Furihata M, Sonobe H, Ohtsuki Y, Ishikawa T, Murakami H, Kurabayashi A, Ogoshi S, Sasaguri S
Abstract excerpt
BACKGROUND: It is generally accepted that cigarette smoking is closely associated with esophageal squamous cell carcinoma. This study investigated the molecular targets of cigarette smoke in carcinogenesis of the esophagus. METHODS: Seventy-four patients with esophageal squamous cell carcinoma (SCC) were grouped according to daily cigarette consumption: heavy smoking group (group H) (n = 26), moderate smoking...
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