Article
High prevalence of p53 gene alterations and protein overexpression in human esophageal cancer: correlation with dietary risk factors in India.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Nov 1997
Gaur D, Arora S, Mathur M, Nath N, Chattopadhaya T K, Ralhan R
Abstract excerpt
Epidemiological studies have demonstrated an association between human esophageal cancer and dietary/nutritional risk factors in developing countries. We examined the expression of p53 protein in 51 cases of esophageal squamous cell carcinomas (ESCCs) and paired normal esophageal tissues by immunohistochemistry. Alterations in the tumor suppressor gene p53 (exons 5-8) were analyzed in 51 cases of ESCC and paired...
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