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Article

Role for HLA class II molecules in HIV-1 suppression and cellular immunity following antiretroviral treatment.

The Journal of clinical investigation - 1 Feb 2001

Malhotra U, Holte S, Dutta S, Berrey M M, Delpit E, Koelle D M, Sette A, Corey L, McElrath M J

Abstract excerpt

HIV-1-infected patients treated early with combination antiretrovirals respond favorably, but not all maintain viral suppression and improved HIV-specific Th function. To understand if genetic factors contribute to this variation, we prospectively evaluated over 18 months 21 early-treated patients stratified by alleles of class II haplotypes. All seven subjects with the DRB1*13-DQB1*06 haplotype, but only 21% of...

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Share to Acquired Immunodeficiency Syndrome
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to CD4 Lymphocyte Count

Share to Gene Products, gag

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Share to HLA-DQ Antigens

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Source

Open in PubMed Open full text

Identifiers

PMID: 11181650
DOI: 10.1172/JCI11275
PMCID: PMC199253

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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