Article
Expression quantitative trait loci mapping identifies new genetic models of glutathione S-transferase variation.
Drug metabolism and disposition: the biological fate of chemicals - 1 Jun 2009
Hayes Kevin R, Young Brandon M, Pletcher Mathew T
Abstract excerpt
Expression quantitative trait loci (eQTL) mapping can be used to identify the genetic variations that underlie inherited differences in gene transcription. We performed eQTL mapping by combining whole genome transcriptional data from the hypothalami of 33 strains of inbred mice with a detailed haplotype map of those same strains, revealing 10,655 trans associations and 31 cis eQTLs. One of the cis associations...
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