Article
The role of MHC class I glycoproteins in the regulation of induction of cell death in immunocytes by malignant melanoma cells.
Proceedings of the National Academy of Sciences of the United States of America - 13 Feb 2001
Fishman D, Irena B, Kellman-Pressman S, Karas M, Segal S
Abstract excerpt
A deranged expression of MHC class I glycoproteins, characteristic of a variety of malignancies, contributes to the ability of cancer to avoid destruction by T cell-mediated immunity. An abrogation of the metastatic capacity of B16 melanoma cells has been achieved by transfecting an MHC class I-encoding vector into class I-deficient B16 melanoma clones [Gorelik, E., Kim, M., Duty, L. & Galili, U. (1993) Clin....
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