Article
Acute cocaine-induced seizures: differential sensitivity of six inbred mouse strains.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Mar 2001
Golden G T, Ferraro T N, Smith G G, Snyder R L, Jones N L, Berrettini W H
Abstract excerpt
Mature male and female mice from six inbred stains were tested for susceptibility to behavioral seizures induced by a single injection of cocaine. Cocaine was injected ip over a range of doses (50-100 mg/kg) and behavior was monitored for 20 minutes. Seizure end points included latency to forelimb or hindlimb clonus, latency to clonic running seizure and latency to jumping bouncing seizure. A range of strain...
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