Chromosomal mapping of loci influencing sensitivity to cocaine-induced seizures in BXD recombinant inbred strains of mice.

doi:10.1007/BF02245099

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Article

Chromosomal mapping of loci influencing sensitivity to cocaine-induced seizures in BXD recombinant inbred strains of mice.

Psychopharmacology - 1 Jan 1995

Miner L L, Marley R J

Abstract excerpt

Among inbred mice, genetic factors mediate differences in sensitivity to the convulsant properties of cocaine; however, the gene(s) underlying cocaine's effects have not been identified. To help elucidate the gene(s) responsible for cocaine seizure susceptibility, we used recombinant inbred-quant...

Topics

Animals
Chromosome Mapping
Cocaine
Dose-Response Relationship, Drug
Genetic Markers
Male
Mice
Mice, Inbred C57BL
Mice, Inbred DBA
Mice, Inbred Strains
Phenotype
Recombination, Genetic
Seizures

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