Article
Psychomotor stimulant effects of cocaine in rats and 15 mouse strains.
Experimental and clinical psychopharmacology - 1 Oct 2011
Thomsen Morgane, Caine S Barak
Abstract excerpt
Relative to intravenous drug self-administration, locomotor activity is easier to measure with high throughput, particularly in mice. Therefore its potential to predict differences in self-administration between genotypes (e.g., targeted mutations, recombinant inbred strains) is appealing, but such predictive value is unverified. The main goal of this study was to evaluate the utility of the locomotor assay for...
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