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Article

Genetic correlations among inbred strain sensitivities to convulsions induced by 9 convulsant drugs.

Brain research - 27 Aug 1990

Kosobud A E, Crabbe J C

Abstract excerpt

Inbred mouse strains differed significantly in sensitivity to convulsions induced by 9 convulsant drugs administered using a timed infusion procedure. Some strains (e.g. BALB/cJ, A/J) were generally seizure-susceptible, while some were generally seizure resistant (e.g. C57BL/6J, SWR/J). However, the overall pattern of strain sensitivities was complex, and depended upon drug and convulsant sign. Five of the drugs...

Topics

Animals
Convulsants
Genetic Predisposition to Disease
Infusions, Intravenous
Male
Mice
Mice, Inbred Strains
Reaction Time
Seizures
Species Specificity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 2078820
DOI: 10.1016/0006-8993(90)90243-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2078820-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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