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Article

Pharmacokinetic and pharmacodynamic analyses of cocaine and its metabolites in behaviorally divergent inbred mouse strains.

Genes, brain, and behavior - 1 Feb 2021

Zhu Jing, Beechinor Ryan J, Thompson Trey, Schorzman Allison N, Zamboni William, Crona Daniel J, Weiner Daniel L, Tarantino Lisa M

Abstract excerpt

Cocaine (COC) is a psychostimulant with a high potential for abuse and addiction. Risk for COC use disorder is driven, in part, by genetic factors. Animal models of addiction-relevant behaviors have proven useful for studying both genetic and nongenetic contributions to drug response. In a previous study, we examined initial locomotor sensitivity to COC in genetically diverse inbred mouse strains. That work...

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Identifiers

PMID: 32383297
DOI: 10.1111/gbb.12666
PMCID: PMC7941260

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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