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Article

Neural sensitivity to pentylenetetrazol convulsions in inbred and selectively bred mice.

Brain research - 2 Oct 1992

Kosobud A E, Cross S J, Crabbe J C

Abstract excerpt

In these experiments, sensitivity to the convulsant drug pentylenetetrazol (PTZ) was measured in 10 inbred mouse strains, and in 4 mouse lines selectively bred for severe (WSP1, WSP2) or minimal (WSR1, WSR2) ethanol withdrawal convulsions. Using a timed infusion procedure, sensitivity to convulsions was assessed by measures of latency to convulsion, effective dose (ED) infused at time of convulsion, and brain...

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Identifiers

PMID: 1450904
DOI: 10.1016/0006-8993(92)91666-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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