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Article

Proline transport in MDCK cells expressing a mutant regulatory subunit of cAMP-dependent protein kinase.

Molecular genetics and metabolism - 1 Jan 2001

Zelikovic I, Wager-Miller J

Abstract excerpt

cAMP-dependent protein kinase (cAK) regulates the activity of several membrane-bound ion channels and carriers. The role of cAK in regulating the transport of osmoprotective amino acids in the distal tubule is unknown. We examined the regulation of Na(+)- and Cl(-)-dependent proline transport in MDCK cells expressing a mutant murine regulatory subunit (RIalpha(AB)) of cAK. For this purpose, MDCK cells were...

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Identifiers

PMID: 11161828
DOI: 10.1006/mgme.2000.3110

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