Article
Regulation of growth in a neoplastic B cell line by transfected subunits of 3',5'-cyclic adenosine monophosphate-dependent protein kinase.
Endocrinology - 1 Nov 1994
Taskén K, Andersson K B, Erikstein B K, Hansson V, Jahnsen T, Blomhoff H K
Abstract excerpt
cAMP inhibits the proliferation of both normal peripheral blood B and T lymphocytes as well as the proliferation of a human neoplastic B precursor cell line (Reh). To positively show that this is mediated via the the catalytic subunit, C alpha, of cAMP-dependent protein kinase, stably transfected Reh cell lines overexpressing C alpha were established. This was achieved by transfection with a construct confering...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
