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Article

Further investigation of linkage disequilibrium SNPs and their ability to identify associated susceptibility loci.

Annals of human genetics - 1 May 2004

North B V, Curtis D, Martin E R, Lai E H, Roses A D, Sham P C

Abstract excerpt

There is currently considerable interest in the use of single-nucleotide polymorphisms (SNPs) to map disease susceptibility genes. The success of this method will depend on a number of factors including the strength of linkage disequilibrium (LD) between marker and disease loci. We used a data set of SNP genotypings in the region of the APOE disease susceptibility locus to investigate the likely usefulness of...

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Identifiers

PMID: 15180704
DOI: 10.1046/j.1529-8817.2004.00086.x

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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