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Article

Haplotype analysis of APOE intragenic SNPs.

BMC neuroscience - 19 Apr 2018

Babenko Vladimir N, Afonnikov Dmitry A, Ignatieva Elena V, Klimov Anton V, Gusev Fedor E, Rogaev Evgeny I

Abstract excerpt

BACKGROUND: APOE ε4 allele is most common genetic risk factor for Alzheimer's disease (AD) and cognitive decline. However, it remains poorly understood why only some carriers of APOE ε4 develop AD and how ethnic variabilities in APOE locus contribute to AD risk. Here, to address the role of APOE haplotypes, we reassessed the diversity of APOE locus in major ethnic groups and in Alzheimer's Disease Neuroimaging...

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Source

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Identifiers

PMID: 29745836
DOI: 10.1186/s12868-018-0413-4
PMCID: PMC5998902

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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