Article
SNPing away at complex diseases: analysis of single-nucleotide polymorphisms around APOE in Alzheimer disease.
American journal of human genetics - 1 Aug 2000
Martin E R, Lai E H, Gilbert J R, Rogala A R, Afshari A J, Riley J, Finch K L, Stevens J F, Livak K J, Slotterbeck B D, Slifer S H, Warren L L, Conneally P M, Schmechel D E, Purvis I, Pericak-Vance M A, Roses A D, Vance J M
Abstract excerpt
There has been great interest in the prospects of using single-nucleotide polymorphisms (SNPs) in the search for complex disease genes, and several initiatives devoted to the identification and mapping of SNPs throughout the human genome are currently underway. However, actual data investigating the use of SNPs for identification of complex disease genes are scarce. To begin to look at issues surrounding the use...
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