Article
Estimating haplotype-disease associations with pooled genotype data.
Genetic epidemiology - 1 Jan 2005
Zeng D, Lin D Y
Abstract excerpt
The genetic dissection of complex human diseases requires large-scale association studies which explore the population associations between genetic variants and disease phenotypes. DNA pooling can substantially reduce the cost of genotyping assays in these studies, and thus enables one to examine a large number of genetic variants on a large number of subjects. The availability of pooled genotype data instead of...
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