Article
Effect of the angiotensin II type 2-receptor gene (+1675 G/A) on left ventricular structure in humans.
Journal of the American College of Cardiology - 1 Jan 2001
Schmieder R E, Erdmann J, Delles C, Jacobi J, Fleck E, Hilgers K, Regitz-Zagrosek V
Abstract excerpt
OBJECTIVES: Our study goal was to analyze whether gene variants of angiotensin II type 2-receptor (AT2-R) modulate the effects of angiotensin II on the left ventricle (LV). BACKGROUND: Experimental data suggest that angiotensin II modifies ventricular growth responses via angiotensin II type 1-receptors (AT1-R) and AT2-R. METHODS: In 120 white, young male subjects with normal or mildly elevated blood pressure, we...
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